ENTIERE IDENTITIES BETWEEN OPHIOCOMINA NIGRA IGKAPPA GENE AND HUMAN IMMUNOGLOBULIN KAPPA LOCUS.NEW ASPECTS OF INVERTEBRATE IGKAPPA GENES (IPA)
DOI:
https://doi.org/10.46545/aijcs.v2i1.199Keywords:
OPHIOCOMINA, HUMAN IMMUNOGLOBULINAbstract
Entiere identities between Invertebrate Ophiocomina nigra IGKappa gene and Human IGK gene are confirmed, in the present work, at the level of immunoglobulin domains (constant and variable). The transcriptome of the Ophuirid : Ophiocomina nigra IGKappa gene was discovered recently(1).Since it was synthesized de novo and cloned in a pUC-GW-Kan plasmid (2) which was a gift of Bo Huang laboratories. The original sequence of the IGKappa gene, after cloning, was the following in 5’-3’ :
Downloads
References
Leclerc, M., Marie, Y., Davoult, D., Jolly, A., de la Grange, P., & Paris, I. G. (2018). A true new gene in ophiocomina nigra: an ophuirid Igkappa gene. J Appl Biotechnol Bioeng, 5(1), 17-18.
Leclerc, M. (2021). Immunol. Lett. Submitted
Hutchinson, A. T., Jones, D. R., Winter, P. M., Tangye, S. G., & Raison, R. L. (2014). Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts. Human immunology, 75(9), 986-990.
Vincent, N et al. (2014). Meta Gene 2, 320-22
Downloads
Published
Issue
Section
License
Copyright (c) 2020 Michel Leclerc
This work is licensed under a Creative Commons Attribution 4.0 International License.
